Search on: CENTRAL TOLERANCE 
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Descriptor English:   Central Tolerance 
Descriptor Spanish:   tolerancia central 
Descriptor Portuguese:   Tolerāncia Central 
Synonyms English:   Tolerance, Central  
Tree Number:   G12.535.425.800.200
Definition English:   The mechanism, in central lymphoid organs (THYMUS; BONE MARROW), that prevents immature lymphocytes from reacting to SELF-ANTIGENS. This is accomplished by CLONAL ANERGY and CLONAL DELETION. 
History Note English:   2012 
Allowable Qualifiers English:  
DE drug effects GE genetics
IM immunology PH physiology
RE radiation effects  
Record Number:   54818 
Unique Identifier:   D061167 

Occurrence in VHL:
 

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